Sex cord-stromal tumors represent about 5 percent of all ovarian cancers. They are formed from cells of the sex cord or mesenchyme (early connective tissue) within the embryonic gonad, and they may contain gonad-related cells (., granulosa cells, Sertoli cells, thecal cells) as well as fibroblasts, which are immature, connective tissue-forming cells. The most common tumors in this category are granulosa stromal cell tumors and Sertoli- or Sertoli-Leydig cell tumors; other related tumors include lipid cell tumors and gynandroblastomas.
Abnormal LFTs do not necessarily indicate any underlying abnormality of function. Traditionally, 'normal' values are defined as being within ± 2 standard deviations of the mean (of a normally distributed range), meaning that just over 95% of a healthy population will fall within the 'normal range', but % of a normal population will be normal outliers lying above it, and a further % will be normal outliers lying below it. However, as liver disease is frequently asymptomatic, this argument should not be used as an excuse for inadequate investigation. Abnormal LFTs are often inadequately investigated - which may miss an early opportunity of identifying and treating chronic liver disease [ 4 ] .