Immune mediated presentations include splenomegaly, uveitis and rheumatoid arthritis. Neurological disorders include increased irritability and aggression (all of which mercury in vaccines alone can induce) depression, confusion, overeating, nerve damage in limbs and face, Bells Palsy, hallucinations, sleep disorders, memory loss decreased concentration, seizures. Secondary disturbances of endocrine-adrenal dysfunction include gonadal deficiencies, hypothyroidism, insulin resistance, hypothalamus and pituitary function. This results in decreasing stimulating hormones for end organs including adrenal, growth hormone, testosterone, estro- gen, anti diuretic hormone.
Since I read an article stating that taking zinc supplement can raise your PSA number I have stopped taking it because my PSA score DID get elevated. I am 77 with a PSA of 18,9 at last reading and have adamantly refused to give a prostate biopsy sample because it will compromise my prostate. The urologist then offered me a 'phi(?) test" requiring a blood sample. The result showed I had a 33% chance of prostate cancer. I'll take those odds. He gave me a digital exam and said the left side of the prostate was hard while the right side was soft. He did not elaborate further and ended my visit. I have noticed that there is no semen when I orgasm with my wife. Is that normal at my age?
A recent case of a 51 year old male with an interest in testosterone replacement illustrates the benefits of the multi-parametric prostate MRI scan. Noting a PSA value of only ng/ml; the digital rectal exam (DRE) identified an area of interest on the left side, albeit, it was not definitive for prostate cancer. Neither the gray scale ultrasound nor Color Flow Doppler ultrasound evaluation suggested any specific abnormality consistent with the area of interest previously identified on DRE. An MRI scan was suggested as the next best step in the evaluation. The scan isolated a region of interest on the left side at the Apex to Middle portion of the prostate gland concordant with the findings on the DRE. Based upon the findings of the MRI scan, a targeted biopsy with 6 needle cores was recommended and implemented. An Antiandrogen was initiated pre-biopsy to mitigate against “needle tracking”. Specifically, an Antiandrogen selectively blocks the receptor on the prostate cell from attracting testosterone as it exits the capsule, thereby, disabling the cells in preparation for cell death or apoptosis. The Pathology evaluation revealed a grade of cancer that was amenable to being treated conservatively or focally. In this case, the failure to use a MRI scan would have exposed this patient to the possibility of missing the cancer altogether; associated with sampling bias, a very real possibility for needle tracking (assuming cancer was found), or worse yet, the go ahead to supplement with testosterone, when in fact, the cancer was missed. Using testosterone in this scenario would have stimulated cancer cells to grow wildly, while causing the PSA to spike abnormally, thereby, making the diagnosis of prostate cancer – a potentially uncontrollable clinical event, albeit, avoidable. Given the expertise of a Urolologic consultation, this case turned out well. The patient is now contemplating a focal treatment with high intensity focused ultrasound with a plan to supplement with testosterone once his cancer has been cured. An inability to document the resolution of prostate cancer by a repeat MRI scan and/or a stable PSA post-operatively will preclude this patient from using testosterone replacement therapy.