Equipoise nejm

More generally, the study highlights the need to rigorously evaluate any assumptions that may influence how clinical trials are designed.  In an accompanying editorial , Drs. Christopher O’Connor and Joseph Rogers write, “In an era of rapid intervention in the catheterization laboratory and a pervasive perception of lack of equipoise, the IABP-SHOCK II investigators should be commended for completing a moderate-sized trial in 3 years at 37 sites.”  They add: “We hope that the results of this trial will galvanize a broadly based mandate to address this devastating clinical problem by reestablishing equipoise and international engagement in research on novel devices and pharmacologic therapies.”

Equipoise nejm

equipoise nejm

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